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After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. <> They can recommend if this is safe for you to do. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Otherwise, call a poison control center right away. Here's some detail on certain side effects this drug may cause. A lack of iron can lead to iron deficiency anaemia if left untreated. Some people only need one treatment course of Injectafer. You will need to talk about the benefits and risks to you and the baby. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Back pain. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. (See also Notes section.). Following an LSD trip, users may experience a sort of 'comedown.'. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. Nose or throat irritation. This is only a brief summary of general information about this medicine. ByDr. FG Trade/E+ sia Getty Images Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Injectafer comes as a liquid solution inside vials. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). In the first group, some people continued taking iron by mouth, while other people took Injectafer. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Last updated on Feb 20, 2023. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Injectafer isnt available in a generic form. Theyll likely have you stop taking the pills while youre using Injectafer. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Its responsible for carrying oxygen throughout your body. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Before taking Injectafer, talk with your doctor about your health history. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Side effects from HRT depend on a number of factors: Hemoglobin is a protein thats found in your RBCs. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. *Patients are calculated based on an estimated annual cumulative dose. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. administered at your doctors office or an infusion center. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Some may be a better fit for you than others. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. If either is present, do not use the liquid. 1 0 obj Iron infusion benefits. MNT is the registered trade mark of Healthline Media. This is not a complete list of side effects and others may occur. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Injectafer and Venofer can cause very similar side effects, but some different ones as well. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. As with all medications, the cost of Injectafer can vary. If you notice other effects not listed above, contact your doctor or pharmacist. Severeside effectsmay end up causing a lot of disruption in a persons life. Pain, swelling, or redness at the injection site may occur. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. It may also cause nervousness, restlessness, and difficulty sleeping in some people. However, be sure to take the dosage your doctor prescribes for you. This information should not be used to decide whether or not to take Venofer or any other medicine. pain in the arms or legs. If you have questions about side effects, call your doctor. If you have diarrhea while youre taking Injectafer, call your doctor. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. I had my first infusion of 1gm 10 days ago. It is very important that your doctor check you closely while you are receiving this medicine. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Learn more about these, as well as the symptoms, diagnosis, and treatments. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. But for other people, doing so could lead to having too much iron in their body. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Which tests can diagnose iron deficiency anemia? I used to get a different type but my . Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Together, you and your doctor can develop a treatment plan thats best for you. There have also been reports of serious allergic reactions to Venofer. Available for Android and iOS devices. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. You can also write a reminder on your calendar. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Details. Source: Wolters Kluwer Health. In Canada - Call your doctor for medical advice about side effects. Its not known how often people taking a treatment other than Injectafer had diarrhea. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. However, many people have no side effects or only have minor side effects. Use Venofer as ordered by your doctor. Dizziness. What is the latest research on the form of cancer Jimmy Carter has? This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. dizziness. Learn how to store and discard medical supplies safely. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. No, you wont need to take iron pills while youre using Injectafer. * This is a partial list of mild side effects from Injectafer. The study also didnt show if one treatment was worse than the other. For some people, it may be OK to continue taking a multivitamin that contains iron. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. muscle pain. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Its caused by your body not having enough iron, which is needed to make hemoglobin. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Keep out of reach of children. All rights reserved. wAd**CgI%"nn{Oa[q{r5 Phosphorus also helps your nerves function properly. This product may contain inactive ingredients, which can cause allergic reactions or other problems. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Keep all medications away from children and pets. But the length of time that this may take varies from person to person. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). If these effects continue or worsen, tell your doctor. The information provided is not intended to replace your healthcare provider's medical advice. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. All of the people took iron by mouth for 2 weeks. Depending on your anemia symptoms, your weight changes may be different than those described here. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. fever. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. upper respiratory infection. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. For people with certain medical implants, such as pacemakers, an MRI may pose an . Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. In the second group, some people switched from taking iron by mouth to taking Injectafer. Learn more about the types of tests and treatment. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. In clinical trials,. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. reese0809 1 yr. ago. This website is intended for use by US patients. Serious side effects should be reported to a physician and/or PharmD for medical advice. Venofer is not for treating other forms of anemia not caused by iron deficiency. Not all possible drug interactions are listed here. There are currently no generic forms of either drug. In one study, people were given either Injectafer or an iron replacement drug called Venofer. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. WebMD provides common contraindications for Venofer Vial. (A medication class is a group of medications that work in a similar way.). To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Discuss the risks and benefits with your doctor. Potential injection site discoloration has happened. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Keep all drugs in a safe place. It is given into a vein for a period of time. Change in taste. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Its not known if Injectafer is safe to take during pregnancy. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Theyll do this by checking certain blood tests. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. (A medication class describes a group of drugs that work in the same way.). The benefit of treating your condition during pregnancy may outweigh any risks. Taking a higher dose than needed can often lead to adverse effects. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. If you have questions about using Injectafer in a child, talk with your doctor. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. It's a more immediate treatment than supplements or dietary changes. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. intense abdominal pain. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You may also report side effects at https://www.fda.gov/medwatch. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Venofer may cause significant hypotension (decreased blood pressure). Read all information given to you. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Feraheme also comes as a liquid thats given by IV infusion. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. This gives a total cumulative dose of 1,500 mg of Injectafer. Injectafer is a brand-name prescription drug. This means you would get two Injectafer doses of 720 mg each. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. % Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. So theres no recommended pediatric dosage for Injectafer. weakness. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. . Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Does Venofer Vial interact with other medications? In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). endobj It depends. 2 0 obj However, diarrhea it isnt very common in people using Injectafer. Infusion times range from less than 20 minutes to up to 4 hours. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Your healthcare provider will watch you closely for 30 minutes after each dose. It can be given as a slow injection over 2 to 5 minutes or as an infusion. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. And this can lead to anemia, including IDA. After the infusion, you can drive yourself home and return to your usual activities. Vomiting. Check with your pharmacist. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Call your doctor for medical advice about side effects. But you kidneys need iron in order to make EPO. All rights reserved. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. The iron released by this drug does pass into human breast milk. If you think there has been an overdose, call your poison control center or get medical care right away. This includes your doctors, nurses, pharmacists, and dentists. The insurance company will review the prior authorization request and decide if the drug will be covered. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Learn about the causes, symptoms, diagnosis, and treatment of this. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Serious side effects from Injectafer arent common, but they can occur. Learn about uses, cost, how it works, and more. Some products that may interact with this drug include: vitamin products, other iron-containing products. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. On day three I had a headache and felt heavy/exhausted, which lasted a few days. A healthcare provider will give you this injection. And this can affect how well those parts of your body are able to work. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: These nutrients include iron, vitamin B12, and folate. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. If you notice any changes to your normal blood pressure, call your doctor right away. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Iron infusions are given directly into a vein. Heart failure: Could a low sodium diet sometimes do more harm than good? This information is not specific medical advice and does not replace information you receive from the healthcare provider. endobj Can poor sleep impact your weight loss goals? stream The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Headache. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). This includes people who: Usually, hypophosphatemia doesnt cause symptoms. With this condition, you also have a low hemoglobin level. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Cancer patients who have anemia and are taking an ESA. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. What Is the Cost of Whole Genome Sequencing (WGS)? Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. I was surprised too but the Dr said it definitely sounds like a reaction. Hemoglobin is a protein thats found inside your red blood cells. But keep in mind that in this study, delayed allergic reaction only occurred in one person. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. A shortage of iron can cause health problems. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Why is the range so wide? If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. So you wont pick up this medication from a pharmacy. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells.

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